Melvin's digital garden

Soft Computing in Bioinformatics

CREATED: 200612290747

  • Granular computing
  • Genetic algorithms ** multiple objective GA ** Pareto optimal solutions ** VEGA, MOGA, NSGA
  • Rough sets ** lower and upper approximations ** discover redundancies and dependencies between features ** discernability matrix -> reducts
  • Rough clustering ** fuzzy clustering ** rough c-means
  • Rough feature selections
  • Focus on clustering, classification, rule mining ** low cost, high precision solution
  • Protein structure ** secondary ** tertiary ** docking
  • Micro array gene expression

selecting a set of relevant genes

identify causal and classification relationships

gene clustering (similar changes)

data (samples) clustering

gene regulatory network discovery

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