Melvin's digital garden


CREATED: 200810200755 Title: Sorting Cancer Karyotypes by Elementary Operations

  • philadelphia chromosome
  • karyotype determined by chromosome painting
  • chromosomal instability in cancer ** errors during mitosis ** rearrangements associated with double strand break
  • analyze evolution of abberation events
  • Mitelma database of cancer karyotypes,
  • Modelling elementary operations ** breakage/fusion ** duplication ** deletion
  • Karyotype sorting problem

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