Ozery-Flato2008

CREATED: 200810200755 Title: Sorting Cancer Karyotypes by Elementary Operations

philadelphia chromosome
karyotype determined by chromosome painting
chromosomal instability in cancer ** errors during mitosis ** rearrangements associated with double strand break
analyze evolution of abberation events
Mitelma database of cancer karyotypes, www.cydas.org
Modelling elementary operations ** breakage/fusion ** duplication ** deletion
Karyotype sorting problem