GeneMANIA

CREATED: 200701021311

• gene function ** what processes ** biochemical function ** when/where expressed ** interactions with other genes
• inspiration from Google set
• using mouse gene expression ** gene expression profile ** gene annotations ** spatial artifacts on microarray
• 230 binary classifications using SVM (radial (Gaussian) kernels, GIST implementation)
• GeneMANIA ** composite kernel W = sum_k alpha_k times w^k ** assign discriminant value f_i in [-1,1] to each gene, f = (I - L)^{-1}y where L = D - W