Epigenomics of murine and adipose cells

murine cells, human adipose stromal cells

histone modifications, transcription factors

Relationship between

• chromatin state, histone modification
• mRNA and miRNA expression
• binding sites of transcription factor

Method

• take pre-adipocytes and adipocytes of human and mouse
• map histone modifications over time
• compare maps and identify enriched transcription factor motifs
• validate regulators of adipose